ABSTRACT
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children, which can be characterized by hyperactivity and(or)impulsivity, inattention, or a combination.The etiology and pathophysiological mechanism of ADHD have not been clarified yet.More and more studies have shown ADHD has intestinal flora disorder, which may affect the occurrence and development of ADHD through microbiome-gut-brain axis (MGBA). Treatment strategies targeting gut microbiota, including probiotics and dietary therapies, are considered to be a novel and effective method for the prevention or treatment of ADHD.This article reviews the changes of intestinal flora and the progress of diet and probiotics in ADHD children, in order to provide new ideas for treatment of ADHD children.
ABSTRACT
Changes in the composition and ratio of the gut microbes may be associated with many diseases, including mild cognitive impairment (MCI). MCI includes amnestic mild cognitive impairment (aMCI) and non-amnestic mild cognitive impairment (non-aMCI). AMCI translates into Alzheimer's disease (AD) risk is higher, so aMCI may be the best stage for the prevention of AD in the future. Studies have shown that modulating the gut microbiota in patients with aMCI can improve their cognitive function.
ABSTRACT
There are trillions of microbes in human gut, which are related to health and diseases closely.In recent years, with the popularization of the concept of microbiome-gut-brain axis, the influence of intestinal microbiota on central nervous system diseases has drawn increasing attention.Gastrointestinal symptoms are common in children with autism spectrum disorder(ASD), and some studies have also indicated that correcting the dysbiosis of gut microbiome can not only improve the gastrointestinal problems, but also alleviate the symptoms of autism to some extent.Therefore, the relationship between intestinal microbes and ASD has attracted researchers′ attention.This review focuses on several kinds of gut microbesmicrotes that have been extensively studied to reveal the relationship between the microbesmicrotes and autism spectrum disorders and their potential pathogenic or protective mechanisms.
ABSTRACT
There are trillions of microbes in human gut, which are related to health and diseases close-ly. In recent years, with the popularization of the concept of microbiome-gut-brain axis, the influence of intesti-nal microbiota on central nervous system diseases has drawn increasing attention. Gastrointestinal symptoms are common in children with autism spectrum disorder ( ASD) , and some studies have also indicated that correc-ting the dysbiosis of gut microbiome can not only improve the gastrointestinal problems, but also alleviate the symptoms of autism to some extent. Therefore, the relationship between intestinal microbes and ASD has attrac-ted researchers' attention. This review focuses on several kinds of gut microbesmicrotes that have been exten-sively studied to reveal the relationship between the microbesmicrotes and autism spectrum disorders and their potential pathogenic or protective mechanisms.